Research Group Members

PhD Students

  • Nesrin Işıl YAŞAR, PhD Candidate
  • Ahmet Tuncer DURAK, PhD Candidate
  • Semra ÖZDEMİR SALİHOĞLU, PhD Candidate
  • Zehra SARICA, PhD Candidate - (co-supervised by Ö. Kürkçüoğlu)
  • Atam Noyan ERÇETİN, PhD Student

MSc Students

  • Havvanur EKİNCİ, MSc Student
  • Ece BAYRAKTAR, MSc Student
  • Sema KOĞAN, MSc Student

 

Research Areas

Computational Chemistry

  • Organocatalytic Reaction Mechanisms
  • Metal-Catalyzed Reaction Mechanisms

Design of Drugs and Drug Delivery Systems Using In Silico Methods

  • Mechanisms of Antibiotic-Resistant Gram (+)/(-) Bacterial Enzymes and Inhibitor Design
  • Mechanism and Inhibitor Design of PAD2 Enzyme Active in Breast Cancer
  • Design of Wound Dressings for Controlled Drug Release
  • Inactivation Mechanism of GABA-AT Enzyme

 

Ongoing Projects

  • TÜBİTAK 113Z218 Project Leader: Illumination of Cyclopropenyum-Activated Dehydration Reaction Mechanisms: A Computational Approach
  • TÜBİTAK 113F342 Project Leader: Born-Oppenheimer Molecular Dynamics of Very Large Biological Systems using Linear Scaling Approximate Quantum Methods
  • TÜBİTAK 115Z502 Project Leader: Illumination of the Deacetylation Reaction Mechanism of O-Acetylpeptidoglycan Esterase (Ape1) Enzyme Using In Silico Methods and Inhibitor Design
  • TÜBİTAK 113M439 Project Consultant: Design of a Controlled Drug Release System for the Topical Treatment of Chronic Inflammatory Skin Diseases: Steroid-Loaded MOF/Pectin-Containing Wound Dressing

 

Completed Projects

  • TÜBİTAK 104T403 (Researcher): A Computational Study on Factors Affecting the Distribution of Products and the Formation of Oxonium/Carbonylium Ylides in the Reaction of Unsaturated Cyclic Acetals and Ketals with Carbenes
  • TÜBİTAK 105E067 (Researcher): A Center of Excellence for Industrial Innovation in Computational Science and Engineering Program
  • ITU-BAP (Leader): A Computational Study on Factors Affecting the Distribution of Products and the Formation of Oxonium/Carbonylium Ylides in the Reaction of Unsaturated Cyclic Acetals and Ketals with Carbenes
  • TÜBİTAK 108T344 (Leader): A Computational Study on the Mechanism of Inactivation of Gamma-Aminobutyric Acid Aminotransferase (GABA-AT) Enzyme with Vigabatrin

 

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